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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice.
Ascorbic Acid, Sodium Fluoride, Vitamin A And Vitamin D
Brand Name
Tri-vite Drops With Fluoride
Generic Name
Ascorbic Acid, Sodium Fluoride, Vitamin A And Vitamin D
Active Ingredient
Ascorbic AcidCategory
Vitamin C [EPC]
Variants
4
Different strengths and dosage forms
| Strength | Form | Route | NDC |
|---|---|---|---|
| 35 mg/mL | SOLUTION | ORAL | 72162-1659 |
| 35 mg/mL | SOLUTION | ORAL | 58657-323 |
| 35 mg/mL | SOLUTION | ORAL | 63629-1141 |
This page is for informational purposes only and does not replace medical advice. Before using any prescription or over-the-counter medication for Tri-vite Drops With Fluoride, you must consult a qualified healthcare professional.
| 35 mg/mL | SOLUTION | ORAL | 58657-324 |
Detailed information about Tri-vite Drops With Fluoride
Ascorbic Acid, also known as Vitamin C, is an essential water-soluble vitamin and antioxidant used to treat scurvy, promote wound healing, and acidify urine. It belongs to the Vitamin C [EPC] and Acidifying Activity [MoA] drug classes.
Patients with a history of kidney stones (nephrolithiasis) or renal failure should use Ascorbic Acid with caution. High doses can lead to the accumulation of oxalate, increasing the risk of stone formation.
No specific dosage adjustments are typically required for patients with liver disease, though overall nutritional status should be monitored.
No specific age-related adjustments are required, though healthcare providers should consider the patient's total dietary intake and renal function.
If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double the dose to catch up.
Signs of acute overdose may include severe diarrhea, nausea, and abdominal cramps. In patients with G6PD deficiency, massive doses may cause hemolysis (breakdown of red blood cells). Seek emergency medical attention or contact a Poison Control Center immediately if an overdose is suspected.
> Important: Follow your healthcare provider's dosing instructions. Do not adjust your dose without medical guidance.
While generally well-tolerated at recommended doses, high intake may cause:
Ascorbic Acid is an essential nutrient, but pharmacological doses require medical supervision. It is important to distinguish between nutritional supplementation and high-dose therapeutic use.
No FDA black box warnings for Ascorbic Acid.
There are no absolute drug-drug contraindications that require complete avoidance; however, specific clinical scenarios require extreme caution.
Ascorbic Acid is excreted into breast milk. While it is safe and necessary for the nursing infant, the American Academy of Pediatrics suggests that maternal intake should stay within the recommended daily limits to avoid potential issues.
Ascorbic Acid is approved for use in children for the treatment of scurvy and as a nutritional supplement. Dosing must be strictly age-appropriate, as children are more sensitive to the gastrointestinal effects of high doses.
Ascorbic Acid acts as an electron donor for enzymes involved in collagen hydroxylation, carnitine biosynthesis, and norepinephrine synthesis. It also acts as a non-enzymatic antioxidant, scavenging free radicals and protecting cellular components from oxidative damage. Its Acidifying Activity [MoA] occurs because it is a weak acid that is partially excreted unchanged in the urine, thereby lowering the pH.
Common questions about Tri-vite Drops With Fluoride
Ascorbic Acid, or Vitamin C, is primarily used to treat and prevent scurvy, a condition caused by a lack of this essential vitamin in the diet. It is also used by healthcare providers to help acidify the urine, which can be beneficial in treating certain types of urinary tract infections or managing specific kidney stones. Many people take it as a dietary supplement to support immune health, wound healing, and the maintenance of healthy skin and blood vessels. Additionally, it may be used to increase the absorption of iron from the diet in patients with iron-deficiency anemia. Always consult your doctor to determine the appropriate use for your specific health needs.
When taken at recommended doses, Ascorbic Acid is generally very safe and well-tolerated by most individuals. However, taking high doses—typically over 2,000 mg per day—can lead to gastrointestinal issues such as nausea, diarrhea, and stomach cramps. Some people may also experience heartburn, headaches, or mild flushing of the skin. If you notice persistent digestive upset or unusual symptoms, it is important to reduce your intake and speak with a healthcare professional. Most side effects are temporary and resolve once the dosage is adjusted.
There is no known direct dangerous interaction between alcohol and Ascorbic Acid. However, chronic or excessive alcohol consumption can interfere with the body's ability to absorb and store Vitamin C, potentially leading to a deficiency over time. If you are taking Ascorbic Acid to treat a medical condition like scurvy, alcohol may slow your recovery by reducing the supplement's effectiveness. It is always best to discuss your alcohol consumption habits with your doctor when starting any new supplement. Moderation is generally advised to ensure optimal nutrient absorption.
Ascorbic Acid is considered safe and is actually essential during pregnancy for the development of the baby's connective tissues and immune system. Most prenatal vitamins contain the Recommended Dietary Allowance (RDA) of Vitamin C, which is usually sufficient. However, taking extremely high doses (megadoses) during pregnancy is not recommended, as it could potentially cause the baby to develop a dependency, leading to 'rebound scurvy' after birth. You should always follow the dosage recommendations provided by your obstetrician. Never start high-dose supplements while pregnant without professional medical guidance.
The time it takes for Ascorbic Acid to work depends on the condition being treated. For those suffering from scurvy, improvements in symptoms like fatigue and bleeding gums can often be seen within 24 to 48 hours of starting treatment. For wound healing or immune support, the effects are more gradual and may take several weeks of consistent use to become apparent. If you are using it to acidify your urine, the pH change typically occurs within a few hours of ingestion. Consistent daily use is necessary to maintain adequate levels in the body.
If you are taking standard doses or getting Vitamin C through your diet, you can stop at any time without issues. However, if you have been taking very high doses (several grams daily) for a long period, your body may have adjusted to clearing the vitamin more quickly. Stopping 'cold turkey' in this specific situation can occasionally cause a temporary drop in Vitamin C levels below normal, a phenomenon sometimes called rebound scurvy. To avoid this, healthcare providers usually recommend gradually tapering off high doses over a week or two. Consult your doctor for a safe discontinuation plan if you have been using high-dose therapy.
If you miss a dose of Ascorbic Acid, simply take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed one and continue with your regular routine. You should not take two doses at once to make up for a missed one, as this can increase the risk of stomach upset or diarrhea. Since Vitamin C is water-soluble and not stored in large amounts, missing a single dose is unlikely to have a major impact on your health. Try to maintain a consistent schedule to get the most benefit from the supplement.
There is no clinical evidence to suggest that Ascorbic Acid causes weight gain. In fact, some research suggests that adequate Vitamin C levels are necessary for efficient fat metabolism during exercise. Because it is a water-soluble vitamin with no caloric value, it does not contribute to fat accumulation in the body. If you notice unexpected weight changes while taking this supplement, it is likely due to other factors such as diet, activity level, or an underlying medical condition. Always discuss significant weight changes with your healthcare provider.
Ascorbic Acid can interact with several medications, so it is important to be cautious. It can increase the absorption of iron and aluminum, which may be a concern for patients with certain kidney or blood disorders. It may also interfere with the effectiveness of blood thinners like warfarin (Coumadin) and certain chemotherapy drugs. Additionally, high doses can affect the accuracy of blood sugar tests for diabetics. Always provide your doctor or pharmacist with a full list of your current medications and supplements before starting Ascorbic Acid.
Yes, Ascorbic Acid is widely available as a generic medication and is also sold under many different brand names and as a store-brand supplement. Generic versions are required by the FDA to have the same quality, strength, and purity as brand-name versions. Because it is an essential vitamin, it is available over-the-counter (OTC) in many forms, including tablets, powders, and liquids. Prescription-strength versions may be used for specific medical treatments, such as high-dose intravenous therapy. Generic versions are typically more cost-effective while providing the same clinical benefits.
Other drugs with the same active ingredient (Ascorbic Acid)
> Warning: Stop taking Ascorbic Acid and call your doctor immediately if you experience any of these.
Prolonged use of very high doses (megadoses) may lead to the development of calcium oxalate kidney stones. There is also a theoretical risk of "rebound scurvy" if high doses are suddenly discontinued, as the body's metabolic clearance mechanisms remain accelerated for a period of time.
No FDA black box warnings for Ascorbic Acid. It is generally recognized as safe (GRAS) when used according to established guidelines.
Report any unusual symptoms to your healthcare provider.
For most patients, routine lab monitoring is not required. However, those on high-dose therapy or those with renal impairment may require:
Ascorbic Acid does not typically interfere with the ability to drive or operate heavy machinery.
Chronic alcohol consumption can deplete Vitamin C levels in the body. While there is no direct contraindication, alcohol may reduce the efficacy of supplementation by impairing intestinal absorption.
If you have been taking very high doses (several grams daily) for a long period, your healthcare provider may suggest a gradual reduction in dose to prevent a temporary deficiency state known as rebound scurvy.
> Important: Discuss all your medical conditions with your healthcare provider before starting Ascorbic Acid.
> Important: Tell your doctor about ALL medications, supplements, and herbal products you are taking.
There is no significant cross-sensitivity reported between Ascorbic Acid and other vitamins or pharmacological classes.
> Important: Your healthcare provider will evaluate your complete medical history before prescribing Ascorbic Acid.
Elderly patients may have a higher prevalence of renal impairment. Healthcare providers should monitor kidney function and ensure that high-dose Vitamin C does not contribute to stone formation or interact with common medications like warfarin.
Patients with a GFR (Glomerular Filtration Rate) below 30 mL/min should avoid high-dose Ascorbic Acid (typically >500 mg/day) due to the risk of secondary oxalosis and kidney stone progression.
No specific adjustments are required for hepatic impairment, though these patients often have underlying nutritional deficiencies that may necessitate supplementation.
> Important: Special populations require individualized medical assessment.
| Parameter | Value |
|---|---|
| Bioavailability | 70%–90% (at low doses) |
| Protein Binding | Low (approx. 25%) |
| Half-life | 10–20 days (stored), 3–4 hours (excess) |
| Tmax | 2–3 hours (oral) |
| Metabolism | Hepatic; oxidized to dehydroascorbate |
| Excretion | Renal (100% of excess) |
Ascorbic Acid is classified as a water-soluble vitamin within the Vitamin C [EPC] group. It is therapeutically categorized as a nutritional supplement and a urinary acidifying agent.