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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice.
Brand Name
Jaysuing Colour Corrector
Generic Name
Glycerin
Active Ingredient
ChamomileCategory
Standardized Chemical Allergen [EPC]
Variants
1
Different strengths and dosage forms
| Strength | Form | Route | NDC |
|---|---|---|---|
| .006 mg/30mg | LIQUID | TOPICAL | 85060-006 |
Detailed information about Jaysuing Colour Corrector
This page is for informational purposes only and does not replace medical advice. Before using any prescription or over-the-counter medication for Jaysuing Colour Corrector, you must consult a qualified healthcare professional.
Chamomile is a standardized plant-derived substance used clinically as a chemical allergen for diagnostic testing and traditionally as a therapeutic agent. It belongs to the Asteraceae family and is classified as a Standardized Chemical Allergen [EPC] for its role in identifying hypersensitivity.
The dosage of Chamomile varies significantly based on the form used and the condition being addressed. Because Chamomile is often sold as a dietary supplement, there is no single "standard" dose, but the following ranges are commonly cited in clinical literature:
Chamomile is generally not recommended for infants or young children without direct medical supervision due to the risk of botulism spores (rarely found in honey-sweetened preparations) and the high risk of allergic sensitization in children with existing atopic dermatitis.
There are no specific dosage adjustments provided by manufacturers for patients with kidney disease. However, since metabolites are renally excreted, patients with Stage 4 or 5 Chronic Kidney Disease (CKD) should use Chamomile with caution and under medical monitoring.
Because Chamomile is metabolized by the liver and may interact with the Cytochrome P450 enzyme system, patients with significant liver cirrhosis or hepatitis should avoid high-dose extracts, as the risk of drug-drug interactions increases significantly.
Elderly patients may be more sensitive to the sedative effects of Chamomile. Healthcare providers typically recommend starting at the lowest possible dose to minimize the risk of dizziness or falls.
If you miss a dose of Chamomile, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up, as this may increase the risk of sedation or gastrointestinal distress.
While Chamomile has a high margin of safety, an overdose (particularly of concentrated extracts) can lead to:
In the event of a suspected overdose, contact your local poison control center or seek emergency medical attention immediately.
> Important: Follow your healthcare provider's dosing instructions. Do not adjust your dose or combine multiple forms of Chamomile (e.g., tea and capsules) without medical guidance.
Most individuals tolerate Chamomile well, particularly when consumed as a tea. However, the following common side effects may occur:
> Warning: Stop taking Chamomile and call your doctor immediately if you experience any of these symptoms, which may indicate a life-threatening allergic reaction.
No FDA black box warnings currently exist for Chamomile extracts or supplements. However, the FDA does require specific labeling for allergenic extracts used in testing, highlighting the risk of systemic allergic reactions including anaphylaxis during the testing procedure. These tests must only be performed in facilities equipped to handle respiratory and cardiac emergencies.
Report any unusual symptoms or persistent side effects to your healthcare provider. Monitoring for allergic symptoms is especially important during the first few days of use.
Chamomile is often perceived as a "gentle" herb, but it possesses potent biological activity that requires caution. The most critical safety concern is the potential for severe allergic reactions. Patients with a history of hay fever or seasonal allergies should be particularly vigilant. Furthermore, Chamomile contains natural coumarins, which may influence blood clotting, especially at high doses.
There are no FDA black box warnings for Chamomile. However, healthcare providers must exercise extreme caution when using standardized Chamomile allergenic extracts for diagnosis, as the procedure itself can trigger a systemic reaction in highly sensitive individuals.
Chamomile can cause drowsiness and may impair your ability to drive or operate heavy machinery. This effect is significantly magnified if Chamomile is taken with alcohol or other sedative medications (e.g., sleep aids, muscle relaxants). Do not engage in hazardous activities until you know how Chamomile affects you.
Combining alcohol with Chamomile is not recommended. Both substances act as central nervous system (CNS) depressants. Concurrent use can lead to excessive sedation, respiratory depression, and impaired coordination.
There is no evidence of a physical withdrawal syndrome associated with stopping Chamomile. However, if you have been using it for chronic anxiety or insomnia, your symptoms may return (rebound) upon discontinuation. It is often best to taper the dose over several days rather than stopping abruptly.
> Important: Discuss all your medical conditions, especially allergies and upcoming surgeries, with your healthcare provider before starting Chamomile.
While few drugs are strictly contraindicated, the following combinations pose a high risk:
For each interaction, the primary mechanism is usually either pharmacodynamic (additive effects on the brain or blood clotting) or pharmacokinetic (competition for liver enzymes like CYP3A4). The management strategy usually involves dose adjustment of the primary medication or complete avoidance of the supplement.
> Important: Tell your doctor about ALL medications, supplements, and herbal products you are taking, including those used occasionally.
Chamomile must NEVER be used in the following circumstances:
Conditions requiring a careful risk-benefit analysis by a physician include:
Patients should be aware of cross-sensitivity with:
If you have reacted to any of these substances in the past, you are more likely to react to Chamomile. Your healthcare provider will evaluate your complete medical history and allergy profile before recommending or prescribing any form of Chamomile.
> Important: Your healthcare provider will evaluate your complete medical history before prescribing or recommending Chamomile.
Chamomile is classified as Pregnancy Category C (by traditional standards). There is a lack of well-controlled human studies regarding its safety during pregnancy. However, historical and animal data suggest that high doses of Chamomile may act as a uterine stimulant, potentially increasing the risk of miscarriage or preterm labor. While occasional consumption of mild Chamomile tea is generally regarded as safe by many midwives, healthcare providers typically advise against the use of concentrated supplements or essential oils during all trimesters. If used near the end of pregnancy, there is a theoretical risk of premature closure of the ductus arteriosus in the fetus, similar to the effects of NSAIDs.
There is limited information on the excretion of Chamomile constituents into breast milk. Small amounts of apigenin likely pass to the infant. While Chamomile is sometimes used by nursing mothers to treat infant colic (via the mother's milk), the safety of this practice has not been established. There is a risk of the infant developing a sensitization or allergic reaction to the proteins in the milk. Nursing mothers should consult a lactation consultant or pediatrician before using Chamomile supplements.
Chamomile is not FDA-approved for use in children under the age of 18 as a drug. As a supplement, it is frequently used for colic and teething, but this carries risks. There have been reported cases of infant botulism associated with herbal teas (though rare) and a significant risk of allergic reactions in children with "atopy" (a genetic tendency toward allergies). Use in children should always be directed by a pediatrician, and the child should be monitored closely for any signs of respiratory distress or rash.
In patients over the age of 65, the primary concern is polypharmacy (taking multiple medications). Older adults are more likely to be on blood thinners or blood pressure medications that interact with Chamomile. Additionally, the sedative effects of apigenin may be more pronounced in the elderly due to age-related changes in liver metabolism and brain sensitivity, increasing the risk of confusion, dizziness, and falls.
For patients with impaired kidney function, the clearance of Chamomile metabolites may be delayed. While no specific GFR (Glomerular Filtration Rate) adjustments are standardized, patients with a GFR below 30 mL/min should limit their intake to avoid potential accumulation of flavonoids.
Patients with Child-Pugh Class B or C hepatic impairment should exercise extreme caution. Since the liver is the primary site for the metabolism of Chamomile's active compounds and the site of potential drug interactions (via CYP enzymes), liver dysfunction can lead to increased toxicity of both Chamomile and other co-administered drugs.
> Important: Special populations require individualized medical assessment to ensure that the benefits of Chamomile outweigh the potential risks.
Chamomile’s pharmacological activity is driven by its diverse chemical profile. The primary molecular mechanism for its sedative effect involves the flavonoid apigenin, which binds competitively to the benzodiazepine receptors (GABA-A) in the brain. Unlike synthetic benzodiazepines, apigenin does not appear to alter the chloride channel opening frequency in the same way, resulting in anxiolysis without significant muscle relaxation or anticonvulsant activity at standard doses.
Its anti-inflammatory action is mediated through the inhibition of prostaglandin E2 (PGE2) and the suppression of cyclooxygenase-2 (COX-2) enzyme activity. The sesquiterpene alpha-bisabolol has been shown to promote the healing of gastric ulcers by protecting the mucous membrane and reducing acid secretion. Furthermore, the blue-pigmented chamazulene (formed during steam distillation) possesses potent antioxidant properties, scavenging free radicals and inhibiting lipid peroxidation.
| Parameter | Value |
|---|---|
| Bioavailability | Low to Moderate (highly dependent on gut flora) |
| Protein Binding | Estimated 70-90% (for apigenin) |
| Half-life | ~1.5 to 2.1 hours |
| Tmax | 1 - 2 hours |
| Metabolism | Hepatic (Glucuronidation, CYP1A2, 3A4 inhibition) |
| Excretion | Renal (primarily as metabolites) |
Chamomile is classified as a Standardized Chemical Allergen [EPC] in the context of diagnostic medicine. In therapeutic contexts, it is categorized as an herbal sedative/antispasmodic. It is related to other Asteraceae-derived substances but is unique in its high concentration of apigenin and specific essential oils.
Common questions about Jaysuing Colour Corrector
Chamomile is used clinically as a standardized allergen extract to diagnose skin allergies through patch testing. In general wellness, it is frequently used to manage symptoms of mild anxiety, improve sleep quality in those with insomnia, and soothe digestive upsets like gas or indigestion. Some healthcare providers also recommend it as a topical wash for skin irritations or as a mouthrinse for chemotherapy-induced sores. However, its use as a treatment for medical conditions should always be discussed with a doctor, especially given the risk of allergic reactions. It is not a substitute for evidence-based treatments for severe anxiety or chronic insomnia.
The most common side effects of Chamomile include mild drowsiness, which can be beneficial at night but may impair daytime activities. Some individuals experience mild gastrointestinal symptoms, such as nausea or a warming sensation in the stomach. When applied to the skin, it can cause redness, itching, or a rash in sensitive people. Because Chamomile is a member of the daisy family, allergic reactions are the most significant risk, ranging from hay fever-like symptoms to severe skin inflammation. Always perform a small skin patch test before using topical Chamomile products extensively.
It is generally advised to avoid combining alcohol with Chamomile. Both alcohol and Chamomile act as central nervous system depressants, meaning they slow down brain activity. When used together, they can cause excessive sedation, extreme sleepiness, and impaired motor coordination, which increases the risk of accidents or falls. In some cases, this combination can also lead to more profound respiratory depression. If you choose to drink alcohol, ensure you are not taking concentrated Chamomile extracts and consult your doctor about your specific risks.
Chamomile is generally considered unsafe in high doses during pregnancy. While a single, weak cup of tea may be acceptable for some, concentrated supplements and essential oils should be avoided because they can act as uterine stimulants. There is a historical concern that high amounts of Chamomile could increase the risk of miscarriage or early labor. Furthermore, its effect on fetal development has not been extensively studied in humans. Pregnant women should always consult their obstetrician before using any herbal product, including Chamomile.
The time it takes for Chamomile to work depends on the desired effect. For relaxation or help with sleep, users typically feel the effects within 30 to 60 minutes after drinking tea or taking a capsule. For digestive relief, such as reducing gas or bloating, the effects may be felt within an hour. However, for more chronic conditions like Generalized Anxiety Disorder, it may take 2 to 4 weeks of consistent daily use to see a significant clinical improvement. If you do not notice a change after several weeks, you should consult your healthcare provider.
Yes, you can generally stop taking Chamomile suddenly without experiencing dangerous withdrawal symptoms like those associated with benzodiazepines. Chamomile does not cause physical dependence in the traditional sense. However, if you have been using it to manage anxiety or sleep issues, those symptoms may return once you stop. If you have been taking very high doses for a long period, it is often a good idea to gradually reduce your intake over a few days to see how your body reacts. Always keep your doctor informed of changes to your supplement regimen.
If you miss a dose of Chamomile, take it as soon as you remember, unless it is nearly time for your next scheduled dose. In that case, skip the missed dose and continue with your regular schedule. Never take two doses at once to make up for a missed one, as this increases the likelihood of side effects like extreme drowsiness or nausea. For those using Chamomile for diagnostic testing, a missed application or a displaced patch must be reported to the allergist immediately. Consistency is key for achieving the best results in therapeutic use.
There is no clinical evidence to suggest that Chamomile causes weight gain. In fact, some studies suggest it may have a very mild beneficial effect on metabolism and blood sugar regulation, although these effects are not strong enough to be used for weight loss. Unlike some pharmaceutical medications for anxiety or depression, Chamomile is not associated with increased appetite or metabolic changes that lead to fat storage. If you experience sudden weight gain while taking Chamomile, it is likely due to another factor, and you should consult your doctor. Monitoring your overall health while on any supplement is important.
Chamomile can interact with several types of medications, so caution is necessary. It is particularly dangerous when combined with blood thinners like warfarin, as it can increase the risk of bleeding. It also interacts with many drugs processed by the liver's CYP450 enzymes, potentially increasing their levels in your blood and leading to toxicity. Furthermore, it should not be combined with other sedatives or sleep aids due to the risk of excessive drowsiness. Always provide your healthcare provider with a full list of your medications before starting Chamomile to prevent dangerous interactions.
Chamomile is a natural plant product and is not a patented drug, so it is available from many different manufacturers under various brand names. In the world of supplements, there is no "generic" vs. "brand name" in the same way as prescription drugs, but quality can vary significantly. When looking for a high-quality product, seek out those that are "standardized" to a specific amount of active ingredients, such as apigenin. For diagnostic use, the standardized allergenic extracts are produced by specialized biological laboratories and are typically ordered directly by healthcare facilities.
Other drugs with the same active ingredient (Chamomile)