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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice.
Calc. Fluor., Calc. Phos., Calc.sulph., Ferrum Phosphoricum, Kali Mur., Kali Phos., Kali Sulph., Mag. Phos., Nat. Mur., Nat. Phos., Nat.sulphuricum, Silicea
Brand Name
Cell Salts
Generic Name
Calc. Fluor., Calc. Phos., Calc.sulph., Ferrum Phosphoricum, Kali Mur., Kali Phos., Kali Sulph., Mag. Phos., Nat. Mur., Nat. Phos., Nat.sulphuricum, Silicea
Active Ingredient
Calcium FluorideCategory
Standardized Insect Venom Allergenic Extract [EPC]
Variants
3
Different strengths and dosage forms
| Strength | Form | Route | NDC |
|---|---|---|---|
| 10 [hp_X]/g | PELLET | ORAL | 55714-2403 |
| 15 [hp_X]/mL | LIQUID | ORAL | 55714-4831 |
| 10 [hp_X]/mL | LIQUID | ORAL | 55714-2402 |
References used for this content
This page is for informational purposes only and does not replace medical advice. Before using any prescription or over-the-counter medication for Cell Salts, you must consult a qualified healthcare professional.
Detailed information about Cell Salts
Calcium Fluoride is a naturally occurring mineral compound primarily utilized for dental health and bone mineralization. It belongs to the class of fluoride-containing minerals and is used to support enamel integrity and skeletal strength.
For general mineral supplementation or dental health support, adult dosages typically range from 0.5 mg to 1.0 mg of fluoride equivalent daily. In specialized dental treatments, higher concentrations may be applied topically by a professional. Always follow the specific instructions provided on the product label or by your dentist.
Pediatric use must be strictly monitored to prevent dental fluorosis (mottling of the teeth).
Patients with significant renal impairment (kidney disease) may have reduced clearance of fluoride, leading to higher systemic levels. Dosage should be adjusted cautiously under medical supervision.
No specific dosage adjustments are generally required for patients with liver disease, as the liver is not the primary organ for fluoride elimination.
Elderly patients should be monitored for bone density changes, but standard adult dosing is typically appropriate unless kidney function is compromised.
Calcium Fluoride supplements should ideally be taken at a different time than high-calcium dairy products or antacids, as calcium can bind with fluoride and reduce its absorption. For dental health, it is often most effective when taken before bedtime after brushing teeth. Oral tablets should be swallowed whole or dissolved in the mouth as directed by the specific formulation.
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.
Signs of acute fluoride overdose include nausea, vomiting, abdominal pain, and hypersalivation (excessive drooling). In severe cases, it can lead to hypocalcemia (low calcium levels) and cardiac arrhythmias. If an overdose is suspected, contact a poison control center or seek emergency medical attention immediately.
> Important: Follow your healthcare provider's dosing instructions. Do not adjust your dose without medical guidance.
When used at appropriate levels, Calcium Fluoride is generally well-tolerated. However, mild gastrointestinal upset, including nausea or a slight metallic taste in the mouth, can occur shortly after ingestion.
Calcium Fluoride is intended for supplemental use and should not replace a balanced diet or standard dental hygiene practices. The safety of this compound depends heavily on the total daily intake of fluoride from all sources, including fluoridated drinking water, toothpaste, and dietary sources.
No FDA black box warnings for Calcium Fluoride.
There are no absolute drug-drug contraindications that require complete avoidance; however, high doses of Calcium Carbonate or Aluminum Hydroxide should not be taken at the same time as Calcium Fluoride, as they can form insoluble complexes that prevent fluoride absorption.
Calcium Fluoride must NEVER be used in the following circumstances:
Calcium Fluoride is classified as FDA Pregnancy Category C. While fluoride crosses the placenta, there is limited evidence that supplemental Calcium Fluoride provides a significant dental benefit to the fetus. It should be used during pregnancy only if clearly needed and recommended by a physician.
Fluoride is excreted in breast milk in very small amounts. The concentration is generally considered too low to provide a dental benefit to the nursing infant, but it is also considered safe for the mother to use at standard doses.
Pediatric use is the most common clinical application for Calcium Fluoride. It is approved for children living in areas with low water fluoridation. Monitoring by a dentist is essential to ensure the child does not develop dental fluorosis.
Calcium Fluoride provides a source of fluoride ions (F-) and calcium ions (Ca2+). The fluoride ion works by replacing the hydroxyl group in bone and tooth hydroxyapatite [Ca10(PO4)6(OH)2] to form fluorapatite [Ca10(PO4)6F2]. Fluorapatite has a lower solubility product than hydroxyapatite, making it more resistant to the demineralization process triggered by bacterial acids in the mouth.
The onset of action for topical effects is immediate upon contact with enamel. Systemic effects on developing teeth and bone occur over months of consistent use. The duration of effect on enamel is semi-permanent as long as the fluorapatite layer remains intact.
| Parameter | Value |
|---|---|
| Bioavailability | 50% - 70% |
| Protein Binding | < 1% |
Common questions about Cell Salts
Calcium Fluoride is primarily used to prevent tooth decay and strengthen the protective enamel layer of the teeth. It works by making the enamel more resistant to acid attacks from plaque bacteria and sugars in the mouth. Additionally, it is sometimes used in mineral supplements to support overall bone density and skeletal health. In some therapeutic traditions, it is also utilized to support the elasticity of connective tissues. Your dentist or doctor may recommend it if you live in an area with low water fluoridation.
The most common side effects of Calcium Fluoride include mild stomach upset, nausea, or a temporary metallic taste in the mouth if taken orally. When used correctly at recommended doses, side effects are quite rare. However, if children ingest too much fluoride over a long period, they may develop dental fluorosis, which appears as white streaks or spots on the teeth. Always ensure that supplements are kept out of reach of children to prevent accidental over-ingestion. If you notice persistent stomach pain, consult your healthcare provider.
There is no known direct interaction between alcohol and Calcium Fluoride that would make the medication dangerous. However, alcohol can interfere with the body's ability to absorb and utilize essential minerals, which might indirectly reduce the benefits of the supplement. Chronic alcohol use is also associated with weakened bone structure, which may counteract the bone-strengthening goals of Calcium Fluoride. It is always best to consume alcohol in moderation and discuss your lifestyle habits with your doctor. Maintaining a healthy diet is key to the supplement's effectiveness.
Calcium Fluoride is generally considered safe during pregnancy when taken at standard nutritional doses, but it should only be used under medical supervision. The FDA classifies it as Category C, meaning that while there are no known risks, comprehensive human studies are limited. Most doctors do not recommend high-dose fluoride supplements during pregnancy because the dental benefits for the developing fetus are not well-established. If you are pregnant or planning to become pregnant, talk to your obstetrician about your total fluoride intake from water and dental products. They will help determine if a supplement is necessary for your specific needs.
The time it takes for Calcium Fluoride to work depends on the intended use. For topical enamel protection, the interaction between fluoride ions and the tooth surface begins almost immediately upon contact. However, for systemic benefits—such as strengthening developing teeth in children or supporting bone density—it may take several months of consistent use to see measurable clinical results. Regular dental checkups are the best way to monitor the effectiveness of fluoride therapy. Consistency is vital for the long-term remineralization process to be successful.
Yes, you can stop taking Calcium Fluoride suddenly without experiencing withdrawal symptoms or physical distress. Unlike some medications that require a tapering period, Calcium Fluoride is a mineral supplement that the body processes as a nutrient. However, once you stop the supplement, the increased protection it provides against tooth decay will gradually diminish over time. If you were prescribed the supplement for a specific medical or dental reason, you should consult your provider before stopping. They can advise you on alternative ways to maintain your dental and bone health.
If you miss a dose of Calcium Fluoride, take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed one and continue with your regular routine. You should never take two doses at once to make up for a missed one, as this can increase the risk of stomach irritation. Missing a single dose will not significantly impact your long-term dental health, but consistency is important for the best results. Setting a daily reminder can help you stay on track with your mineral supplementation.
There is no scientific evidence to suggest that Calcium Fluoride causes weight gain. As a mineral compound, it does not contain calories and does not affect the metabolic processes that typically lead to changes in body weight. If you experience unexpected weight gain while taking this or any other supplement, it is likely due to other factors such as diet, activity level, or an underlying medical condition. You should discuss any significant changes in your weight with your healthcare provider. They can help identify the root cause and ensure your overall health is managed correctly.
Calcium Fluoride can interact with certain other medications, particularly those containing high levels of calcium, aluminum, or magnesium, such as antacids and certain vitamins. These minerals can bind to fluoride in the digestive tract and prevent it from being absorbed into your system. To avoid this, it is recommended to take Calcium Fluoride at least two hours before or after taking other mineral supplements or antacids. It may also interact with certain antibiotics like tetracycline. Always provide your doctor or pharmacist with a full list of all medications and supplements you are currently taking.
Calcium Fluoride itself is a basic mineral compound and is widely available in various generic forms, including as a dietary supplement and in homeopathic preparations. It is not typically sold as a high-cost brand-name prescription drug in the same way as complex pharmaceuticals. You can find it in many health food stores and pharmacies under its chemical name or as part of a multi-mineral complex. When purchasing, ensure the product is from a reputable manufacturer that follows Good Manufacturing Practices (GMP). Your healthcare provider can recommend a specific brand or formulation that meets your clinical needs.
Other drugs with the same active ingredient (Calcium Fluoride)
> Warning: Stop taking Calcium Fluoride and call your doctor immediately if you experience any of these:
The most significant long-term risk is Dental Fluorosis, which occurs during tooth development in children, resulting in white spots or staining on the enamel. In adults, chronic extreme over-ingestion can lead to Skeletal Fluorosis, a condition where bones become overly dense and brittle, increasing the risk of fractures and joint stiffness.
No FDA black box warnings are currently issued for Calcium Fluoride when used as a mineral supplement or dental prophylactic. However, it must be kept out of reach of children to prevent accidental acute toxicity.
Report any unusual symptoms to your healthcare provider.
For patients on long-term, high-dose fluoride therapy, healthcare providers may monitor:
Calcium Fluoride does not typically cause drowsiness or cognitive impairment and is considered safe for individuals who drive or operate heavy machinery.
There are no known direct interactions between alcohol and Calcium Fluoride. However, excessive alcohol consumption can impair mineral metabolism and overall bone health.
Calcium Fluoride can generally be discontinued without a tapering period. However, the protective dental benefits will diminish once the supplemental fluoride is no longer present in the oral environment.
> Important: Discuss all your medical conditions with your healthcare provider before starting Calcium Fluoride.
Calcium Fluoride does not typically interfere with common blood chemistry panels, though it will obviously increase measured serum and urine fluoride levels.
> Important: Tell your doctor about ALL medications, supplements, and herbal products you are taking.
There is no significant cross-sensitivity reported between Calcium Fluoride and other major drug classes.
> Important: Your healthcare provider will evaluate your complete medical history before prescribing Calcium Fluoride.
As the kidneys are responsible for 50% of fluoride excretion, patients with a GFR below 30 mL/min should avoid fluoride supplements unless specifically directed by a nephrologist.
No specific adjustments are required for hepatic impairment, as the liver does not play a major role in the processing of this mineral.
> Important: Special populations require individualized medical assessment.
| Tmax | 30 - 60 minutes |
| Metabolism | None (Ionic dissociation) |
| Excretion | Renal (50%), Fecal (trace) |
Calcium Fluoride is classified as a Mineral/Fluoride Supplement. It is related to other fluoride salts such as Sodium Fluoride (NaF) and Stannous Fluoride (SnF2).