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Medical Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice.
Other
Anagallis Arvensis Whole, commonly known as Scarlet Pimpernel, is a botanical substance used primarily in homeopathic medicine for skin conditions and hepatobiliary support. It belongs to the Primulaceae family and contains active triterpenoid saponins.
Name
Anagallis Arvensis Whole
Raw Name
ANAGALLIS ARVENSIS WHOLE
Category
Other
Drug Count
3
Variant Count
15
Last Verified
February 17, 2026
About Anagallis Arvensis Whole
Anagallis Arvensis Whole, commonly known as Scarlet Pimpernel, is a botanical substance used primarily in homeopathic medicine for skin conditions and hepatobiliary support. It belongs to the Primulaceae family and contains active triterpenoid saponins.
Detailed information about Anagallis Arvensis Whole
References used for this content
This page is for informational purposes only and does not replace medical advice. Consult a qualified healthcare professional before using any medication containing Anagallis Arvensis Whole.
Anagallis Arvensis Whole refers to the entire plant of Anagallis arvensis, a member of the Primulaceae family commonly known as the Scarlet Pimpernel. In a clinical and pharmacological context, this substance is primarily utilized within the framework of homeopathic medicine and traditional herbalism. It is classified as a botanical therapeutic agent. While not an FDA-approved pharmaceutical drug in the sense of a synthetic chemical entity like an ACE inhibitor, it is recognized within the Homeopathic Pharmacopoeia of the United States (HPUS).
Historically, the plant has been used since the time of ancient Greece, where it was mentioned by Dioscorides for its potential effects on the eyes and liver. In modern clinical practice, healthcare providers who specialize in integrative or homeopathic medicine may prescribe Anagallis Arvensis Whole for a variety of conditions, most notably those involving the skin (such as pruritus or itchy skin) and the hepatobiliary system (the liver and gallbladder). The plant is characterized by its small, five-lobed flowers that close in response to changes in atmospheric pressure, earning it the nickname 'Poor Man's Weatherglass.'
From a pharmacological perspective, Anagallis Arvensis Whole contains several bioactive compounds, including triterpenoid saponins (specifically anagalloside), flavonoids, tannins, and small amounts of volatile oils. These components contribute to its biological activity, though they also necessitate caution due to potential toxicity if consumed in raw, non-homeopathic quantities. It is essential to understand that in the United States, homeopathic preparations of Anagallis Arvensis are regulated as drugs under the Federal Food, Drug, and Cosmetic Act, but they are not subject to the same pre-market approval process as conventional new drugs.
The mechanism of action for Anagallis Arvensis Whole varies significantly depending on the concentration and preparation of the extract. At a molecular level, the primary active constituents are triterpenoid saponins. These molecules are known for their ability to interact with cellular membranes. In traditional pharmacological terms, saponins can act as secretolytics (substances that promote the secretion of mucus) and may exert an irritant effect on mucous membranes, which is why historical uses included inducing diuresis (increased urination) or expectoration.
In homeopathic dilutions, the mechanism is based on the 'Law of Similars,' where extremely minute doses are used to stimulate the body's self-healing response. However, from a biochemical standpoint, the saponins found in Anagallis arvensis have been studied for their antifungal and antiviral properties. Research suggests that these saponins may disrupt the lipid envelopes of certain viruses or the cell walls of fungi. Furthermore, some studies indicate that extracts may have an inhibitory effect on certain enzymes, though the clinical significance of this in humans requires further investigation.
When applied topically or taken in regulated homeopathic doses, it is thought to modulate the inflammatory response in the skin. This may occur through the stabilization of mast cells or the inhibition of certain pro-inflammatory cytokines, which helps explain its traditional use in treating itchy rashes and localized dermatitis. In the liver, it is traditionally believed to support bile flow (choleretic effect), though the exact receptor-mediated pathway for this action remains largely uncharacterized in modern clinical literature.
Detailed pharmacokinetic data for Anagallis Arvensis Whole as a complex botanical mixture is limited compared to purified synthetic drugs. However, based on the properties of its primary components (saponins and flavonoids), the following profile can be outlined:
Anagallis Arvensis Whole is utilized for several specific indications within the realm of integrative medicine:
Anagallis Arvensis Whole is available in several preparations:
> Important: Only your healthcare provider can determine if Anagallis Arvensis Whole is right for your specific condition. Do not attempt to self-diagnose or treat serious medical conditions with botanical extracts without professional guidance.
Dosage for Anagallis Arvensis Whole is highly dependent on the preparation type and the potency of the product. Because it is primarily used in homeopathy, the 'dose' refers more to the frequency of administration rather than the milligram weight of the active ingredient.
Anagallis Arvensis Whole is not generally recommended for use in infants or very young children without direct supervision from a pediatric specialist or a qualified homeopathic practitioner.
Patients with significant kidney disease should use Anagallis Arvensis Whole with caution. While homeopathic dilutions contain negligible amounts of plant material, concentrated tinctures may contain saponins that could potentially irritate the renal parenchyma (kidney tissue). No specific GFR-based (Glomerular Filtration Rate) adjustments are available, but lower frequencies of dosing are advised.
Given its traditional use for liver conditions, patients with active hepatitis or cirrhosis must be closely monitored. While it is intended to support the liver, high doses of raw extract can be hepatotoxic (damaging to the liver). Always consult a hepatologist before adding botanical supplements to a liver-care regimen.
Elderly patients may be more sensitive to the effects of botanical extracts. It is generally recommended to start at the lowest possible potency (e.g., 30C) to assess tolerance and minimize the risk of 'homeopathic aggravation' (a temporary worsening of symptoms before improvement).
To ensure maximum efficacy and safety, follow these specific instructions:
If you miss a dose of Anagallis Arvensis Whole, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.
An overdose of high-potency homeopathic pellets (e.g., 30C) is unlikely to cause severe toxicity due to the extreme dilution. However, an overdose of the raw plant or a concentrated mother tincture can be serious.
Signs of Overdose (Concentrated Forms):
In the event of an overdose involving concentrated extracts, contact your local poison control center or seek emergency medical attention immediately.
> Important: Follow your healthcare provider's dosing instructions exactly. Do not adjust your dose or frequency without medical guidance.
While Anagallis Arvensis Whole is generally well-tolerated in homeopathic dilutions, some individuals may experience mild reactions. The most common 'side effect' reported in homeopathic literature is a temporary intensification of the symptoms being treated, known as a 'healing crisis' or 'homeopathic aggravation.'
While rare with regulated homeopathic products, serious reactions can occur, particularly if an individual has an undiagnosed allergy to the Primulaceae family.
> Warning: Stop taking Anagallis Arvensis Whole and call your doctor immediately if you experience any of the following:
There is limited clinical data regarding the long-term use of Anagallis Arvensis Whole. In homeopathic philosophy, remedies are generally not intended for indefinite use; they are stopped once the symptoms resolve. Prolonged use of concentrated tinctures could theoretically lead to chronic irritation of the digestive tract or kidneys due to the cumulative effect of saponins and tannins. It is vital to have regular check-ups with a healthcare provider if you are using any botanical product for more than a few weeks.
No FDA black box warnings exist for Anagallis Arvensis Whole. However, it is important to note that the FDA does not evaluate homeopathic drugs for safety or effectiveness to the same standards as conventional pharmaceuticals. The lack of a black box warning does not imply that the product is devoid of risk.
Report any unusual symptoms or persistent side effects to your healthcare provider. You may also report side effects to the FDA at 1-800-FDA-1088 or via the MedWatch website.
Anagallis Arvensis Whole should be used as a complementary approach and not as a replacement for conventional medical treatment, especially for serious conditions. Patients must ensure they are using a product that has been manufactured according to Good Manufacturing Practices (GMP) to avoid contamination or incorrect concentrations.
No FDA black box warnings for Anagallis Arvensis Whole.
For patients using Anagallis Arvensis Whole for chronic conditions or in lower dilutions (tinctures), the following monitoring may be recommended by a doctor:
In most cases, Anagallis Arvensis Whole does not interfere with the ability to drive or operate machinery. However, if you experience dizziness or unexpected drowsiness after taking a dose, avoid these activities until you know how the substance affects you.
Many liquid preparations of Anagallis Arvensis are tinctures containing a significant percentage of ethanol (alcohol). Patients who are sensitive to alcohol, those taking disulfiram, or those with a history of alcohol use disorder should opt for pellet forms (sucrose/lactose-based) instead of liquid dilutions.
There is no known withdrawal syndrome associated with Anagallis Arvensis Whole. However, it is generally recommended to taper off the frequency of doses as symptoms improve rather than stopping abruptly if you have been taking it for an extended period. If symptoms return after discontinuation, consult your healthcare provider for a re-evaluation.
> Important: Discuss all your medical conditions, including any history of allergies or organ disease, with your healthcare provider before starting Anagallis Arvensis Whole.
While there are no documented 'lethal' drug interactions for Anagallis Arvensis Whole, it should not be used concurrently with:
Most interactions with Anagallis Arvensis Whole are pharmacodynamic, meaning the herb and the drug have similar or opposing effects on the body (e.g., two substances both causing diuresis). There is less evidence for pharmacokinetic interactions (such as CYP450 enzyme inhibition), though the flavonoids in the plant could theoretically interfere with the metabolism of drugs processed by the liver if taken in large quantities.
> Important: Tell your doctor about ALL medications, supplements, and herbal products you are taking. A complete list helps prevent potentially dangerous interactions.
Anagallis Arvensis Whole must NEVER be used in the following circumstances:
Conditions requiring careful risk-benefit analysis by a healthcare professional:
Patients who react to Primrose (Primula) are highly likely to react to Anagallis Arvensis. There is also a theoretical cross-sensitivity with other saponin-containing plants, although this is less common. If you have a history of 'contact allergies' to various garden plants, exercise extreme caution when using topical or oral forms of this remedy.
> Important: Your healthcare provider will evaluate your complete medical history, including any underlying conditions or allergies, before determining if Anagallis Arvensis Whole is safe for you.
There is insufficient high-quality clinical evidence to determine the safety of Anagallis Arvensis Whole during pregnancy. In traditional herbal medicine, some saponin-containing plants were avoided during pregnancy due to the theoretical risk of uterine stimulation or interference with hormonal balance. While homeopathic dilutions (30C) contain virtually no molecules of the original plant and are generally considered low-risk, they should still only be used under the guidance of a healthcare provider. Avoid concentrated tinctures or raw plant material entirely during all trimesters.
It is unknown whether the active constituents of Anagallis Arvensis Whole pass into breast milk. Because the metabolic and excretory systems of a nursing infant are immature, there is a risk that even small amounts of botanical compounds could cause digestive upset or allergic reactions in the baby. Most practitioners recommend avoiding the use of this substance while breastfeeding unless the benefits clearly outweigh the risks.
Anagallis Arvensis Whole is sometimes used in older children for the treatment of itchy skin conditions. However, the dose must be carefully adjusted. Children are more susceptible to the irritant effects of saponins and the alcohol content in tinctures. Always use alcohol-free (glycerite or pellet) forms for children. It is NOT approved for the treatment of serious pediatric illnesses, and a doctor should always be consulted for any rash in a child to rule out infectious causes.
Older adults often have reduced renal and hepatic clearance, which can lead to a slower elimination of botanical compounds. Additionally, the elderly are more likely to be taking multiple prescription medications (polypharmacy), increasing the risk of drug-herb interactions. In the geriatric population, start with the highest possible dilution (e.g., 30C or 200C) to minimize the risk of side effects. Monitor for any signs of dizziness or changes in blood pressure.
For patients with mild to moderate renal impairment, the frequency of dosing should be reduced. The kidneys are a primary route for the excretion of saponin metabolites. In cases of severe impairment (GFR < 30 mL/min), the use of non-homeopathic (concentrated) extracts is contraindicated. Homeopathic pellets are generally considered safe but should still be used under medical supervision.
Patients with liver impairment (Child-Pugh Class B or C) should avoid concentrated tinctures of Anagallis Arvensis. While the plant has a history of use in liver 'cleansing,' an impaired liver may not be able to process the plant's chemical constituents effectively, potentially leading to further liver injury. If use is deemed necessary, liver enzymes should be monitored every 2-4 weeks.
> Important: Special populations require an individualized medical assessment to ensure that any treatment, including botanical remedies, is safe and appropriate.
Anagallis Arvensis Whole exerts its effects through a complex interplay of its phytochemical constituents. The primary active components are triterpenoid saponins, specifically anagalloside, alongside flavonoids (like quercetin) and tannins.
The dose-response relationship for Anagallis Arvensis is non-linear, especially in homeopathic applications. In low dilutions (tinctures), the effect is primarily biochemical and irritant. In high dilutions (homeopathic), the effect is thought to be regulatory. The time to onset for skin itching relief can be rapid (within 30-60 minutes), while the treatment of chronic liver or joint issues may take several weeks of consistent use.
| Parameter | Value |
|---|---|
| Bioavailability | Low (Oral Saponins < 5%) |
| Protein Binding | Unknown (Estimated Moderate) |
| Half-life | Not Formally Established (Estimated 4-8 hours) |
| Tmax | 1-2 hours (for flavonoids) |
| Metabolism | Hepatic (Phase II Conjugation) and Gut Flora Hydrolysis |
| Excretion | Renal (approx. 40%), Biliary/Fecal (approx. 60%) |
Anagallis Arvensis Whole is classified as a Botanical Extract and a Homeopathic Remedy. Within the homeopathic system, it is often grouped with other skin and liver remedies such as Sulphur or Chelidonium majus.
Medications containing this ingredient
Common questions about Anagallis Arvensis Whole
Anagallis Arvensis Whole is primarily used in homeopathic medicine to treat various skin conditions characterized by intense itching, such as eczema, pruritus, and vesicular (blister-like) eruptions. It is particularly noted for its effectiveness in treating itching on the hands and fingers. Additionally, it is used traditionally to support liver and gallbladder health, helping to promote bile flow and address symptoms associated with gallstones. Some practitioners also use it for minor joint pains related to gout. It is important to consult a healthcare provider to ensure it is appropriate for your specific symptoms.
When taken in standard homeopathic dilutions, side effects are rare but can include a temporary worsening of symptoms, known as a homeopathic aggravation. Topical application may cause mild skin redness, tingling, or localized irritation in sensitive individuals. If taken as a concentrated tincture, some people may experience mild nausea, stomach upset, or increased salivation due to the plant's natural saponins and tannins. Most of these effects are mild and resolve quickly once the remedy is discontinued. Always report any persistent or severe side effects to your doctor immediately.
There is no direct chemical interaction between alcohol and the active components of Anagallis Arvensis Whole. However, many liquid forms of this remedy are tinctures that already contain a high percentage of alcohol (ethanol). Consuming additional alcohol may increase the risk of stomach irritation or liver stress, especially if you are using the remedy for liver support. Furthermore, alcohol can sometimes interfere with the intended action of homeopathic medicines. It is generally recommended to limit alcohol consumption while undergoing treatment with botanical remedies.
The safety of Anagallis Arvensis Whole during pregnancy has not been established through rigorous clinical trials. Because the raw plant contains saponins which could theoretically affect uterine tone or hormonal balance, its use is generally discouraged for pregnant women. While highly diluted homeopathic pellets (like 30C) contain very little of the original substance, they should still only be used under the direct supervision of a qualified healthcare professional. Always prioritize conventional prenatal care and discuss any supplements with your obstetrician. Avoid all concentrated extracts or raw forms of the plant during pregnancy.
The time it takes for Anagallis Arvensis Whole to work depends on the condition being treated and the form used. For acute skin itching, some patients report relief within 30 minutes to an hour after taking a homeopathic dose or applying a topical cream. For more chronic conditions, such as long-standing eczema or liver support, it may take two to four weeks of consistent use before significant improvements are noticed. If your symptoms do not improve or if they get worse after a week of use, you should consult your healthcare provider for a different treatment approach.
Yes, you can generally stop taking Anagallis Arvensis Whole suddenly, as it is not known to cause physical dependence or withdrawal symptoms. In homeopathic practice, it is actually recommended to stop taking the remedy once your symptoms have significantly improved or resolved. Continuing to take a homeopathic remedy after the symptoms are gone can sometimes cause the symptoms to return (a 'proving'). If you are using it for a chronic condition, it is best to discuss a tapering schedule or a long-term management plan with your healthcare provider.
If you miss a dose of Anagallis Arvensis Whole, simply take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed one and continue with your regular routine. There is no need to take a double dose to make up for the one you missed. Because homeopathic remedies work by stimulating a response in the body, missing a single dose is unlikely to significantly impact the overall success of the treatment. Just try to stay as consistent as possible with your remaining doses.
There is no clinical evidence to suggest that Anagallis Arvensis Whole causes weight gain. The active components (saponins, flavonoids) do not have a known effect on metabolic rate, fat storage, or appetite in a way that would lead to increased weight. In fact, because it has been used traditionally as a mild diuretic to reduce water retention, some individuals might notice a slight, temporary decrease in water weight. If you experience unexpected or rapid weight gain while taking this or any other supplement, you should consult your doctor to rule out other underlying medical conditions.
Anagallis Arvensis Whole can interact with certain medications, particularly if taken in concentrated forms. It may increase the effects of diuretic drugs or interfere with medications for diabetes or blood clotting. However, high-potency homeopathic pellets (30C and above) are generally considered safe to take alongside most prescription drugs because they contain so little of the active plant material. Regardless of the form, you should always provide your doctor and pharmacist with a full list of all medications and supplements you are taking to ensure there are no specific risks for you.
Anagallis Arvensis Whole is a botanical substance, so the term 'generic' does not apply in the same way it does to synthetic prescription drugs. However, it is available from many different manufacturers of homeopathic and herbal products. When purchasing, look for the name 'Anagallis arvensis' on the label and ensure the product lists its potency (e.g., 6X, 30C). It is important to buy from reputable companies that follow the standards of the Homeopathic Pharmacopoeia of the United States (HPUS) to ensure you are getting a high-quality, standardized product.